Signal integration allows plants to reconcile competing growth and survival needs under intricate environments. This session aims at describing how hormonal, environmental, and stress-related signals are integrated at the molecular and cellular levels. Participants will be informed about crosstalk between abscisic acid, salicylic acid, jasmonates, and ethylene in growth and defense regulation. The session emphasizes transcription factors and gene regulatory networks in orchestrating responses. Scientists will explain how abiotic stresses such as salinity and drought are combined with pathogen responses to refine immunity. Systems biology strategies such as transcriptome and metabolome analysis will be explained in order to chart signaling networks. Participants will also learn how plants maximize growth when faced with scarce resources by repressing or activating metabolic pathways. Applications include crop engineering with fine-tuned signaling to tolerate multiple stresses at once. This session connects molecular biology, physiology, and computational modeling to provide a comprehensive overview of how plants realize adaptive responses.