Plant genomics and gene editing have dramatically changed how researchers examine and enhance crops. During this session, genome sequencing technologies, functional genomics, and gene editing tools application will be discussed. The session will inform participants on how CRISPR facilitates the targeted modification of plant genomes to enhance desired traits. The session emphasizes how genomics helps to reveal genetic diversity and trait mapping. Researchers will share genomics-led breeding case studies on yield, nutrition, and resilience. Participants will learn about the use of bioinformatics methods for the analysis of genomic data. The session also highlights the convergence of transcriptomics, proteomics, and epigenomics into functional investigations. Participants will learn about how systems biology offers a comprehensive representation of gene networks and plant functions. Ethical and regulatory concerns on genome editing in agriculture will be raised. This session connects molecular biology, genetics, and plant science, offering powerful tools to drive crop improvement for food security in the future.